Three liver transplants were successfully performed at IRCCS ISMETT in Palermo using hepatitis C virus (HCV)-positive donor organs.
Three liver transplants were successfully performed at IRCCS ISMETT in Palermo using hepatitis C virus (HCV)-positive donor organs. For the first time, a patient not suffering from HCV could receive an HCV-positive donor organ.
Salvatore Gruttadauria, Director of the Department for the Treatment and Study of Abdominal Diseases and Abdominal Transplantation of ISMETT noted, “Over the past few years, we had already performed liver transplants using grafts procured from donors with HCV. However, in the previous cases before this last series of transplants, there were no signs of the disease in the liver, and the recipients were all HCV-infected.”
Overall, the survival rate in these patients was not lower than those reported for patients receiving a liver not infected by HCV. In these new cases, there was a sustained virology response equivalent to recovery from the HCV infection. “The use of these organs that until a few years ago were considered not suitable for transplant,” commented Angelo Luca, CEO of ISMETT, “is a new, important tool to fight the shortage of organ donors, and will allow us to further reduce mortality of patients on the waiting list.”